SCI Journal Articles* (WoS Researcher ID: G-6092-2013 )

26. Tsogtbaatar K., Sousa D.A., Ferreira D., Tevlek A., Aydın H.M., Çelik E., Rodrigues L., 2021. In vitro selection of DNA aptamers against human osteosarcomaa. Investigational New Drugs, DOI: 10.1007/s10637-021-01161-y.

25. Koçer İ., Cox E.C., DeLisa M.P., Çelik E., 2021. Effects of variable domain orientation on anti-HER2 single-chain variable fragment antibody expressed in the Escherichia coli cytoplasm. Biotechnology Progress, 37, 2, e3102.

24. Akdogan M., Çelik E., 2021. Enhanced production of poly(3-hydroxybutyrate-co-3-hydroxyvalerate) biopolymer by recombinant Bacillus megaterium in fed-batch bioreactors. Bioprocess and Biosystems Engineering, 44, 403-416.

23. Altun E., Çelik E., Yavuz Ersan H., 2020. Tailoring the Microbial Community for Improving the Biodegradation of Chitosan Films in Composting Environment, Journal of Polymers and the Environment, 28, 1548–1559.

22. Yildirim D., Kip Ç., Tsogtbaatar K., Koçer I., Çelik E., Tuncel A., 2020. Microfluidic immobilized metal affinity chromatography based on Ti(IV)-decorated silica microspheres for purification of phosphoproteins, Journal of Chromatography B, 1140, 122010.

21. Gökçal B., Kip C., Sahinbas D., Çelik E., Tuncel A., 2020. Silica microspheres functionalized with the iminodiacetic acid/copper(II) complex as a peroxidase mimic for use in metal affinity chromatography -based colorimetric determination of histidine-tagged proteins. Microchimica Acta, 187, 121.

20. Kip Ç., Babacan Tosun R., Alpaslan S., Koçer I., Çelik E., Tuncel A., 2019. Ni(II)-decorated porous titania microspheres as a stationary phase for column chromatography applications: Highly selective purification of hemoglobin from human blood. Talanta, 200, 100-106.

19. Kip Ç., Gülüşür H., Çelik E., Usta D.D., Tuncel A., 2019. Isolation of RNA and beta-NAD by phenylboronic acid functionalized, monodisperse-porous silica microspheres as sorbent in batch and microfluidic boronate affinity systems. Colloids and Surfaces B: Biointerfaces, 174, 333-342.

18. Akdogan M., Çelik E., 2018. Purification and characterization of polyhydroxyalkanoate (PHA) from Bacillus megaterium strain using various dehydration techniques. Journal of Chemical Technology & Biotechnology, 93, 2292-2298.

17. Salimi K, Usta DD, Koçer I,  Çelik E, Tuncel A, 2018. Protein A and protein A/G coupled magnetic SiO2 microspheres for affinity purification of immunoglobulin G. International Journal of Biological Macromolecules, 111, 178-185.

16. Salimi K., Usta D.D., Koçer I., Çelik E. , Tuncel A., 2017. Highly selective magnetic affinity purification of histidine-tagged proteins by Ni 2+ carrying monodisperse composite microspheres. RSC Advances, 7, 8718-8726.

15. Yildirim Z., Çelik E., 2016. Periplasmic and extracellular production of cellulase from recombinant Escherichia coli cells. Journal of Chemical Technology & Biotechnology, Doi: 10.1002 /jctb.5008 .

14. Çelik, E. , Ollis, A.A., Lasanajak,Y., Fisher, A.C., Gur, G., Smith D.F., DeLisa, M.P. 2015. Glycoarrays with engineered phages displaying structurally diverse oligosaccharides enable high-throughput detection of glycan-protein interactions. Biotechnology Journal, 10(1),199-209.

13. Baker, J.L., Çelik, E., DeLisa, M.P., 2013. Expanding the glycoengineering toolbox: the rise of bacterial N-linked protein glycosylation. Trends in Biotechnology, 31, 313-323.

12. Çelik, E., Çalik, P., 2012. Production of recombinant proteins by yeast cells. Biotechnology Advances. 30, 1108-1118. Invited review.

11. Fisher, A.C., Haitjema, C.H., Guarino, C., Çelik, E.,  Endicott, C.E., Reading, C.A., Merritt,  J.H.,  Ptak, C.A., Zhang, S., DeLisa, M.P., 2011. Production of secretory and extracellular N -linked glycoproteins in Escherichia coli. Applied and Environmental Microbiology , 77, 871-881. 

10. Çelik, E., Fisher, A.C., Guarino, C., Mansell, T.J., DeLisa, M.P., 2010 . A filamentous phage display system for N -linked glycoproteins. Protein Science , 19, 2006-2013. (Selected as journal spotlight article).

9.  Çelik, E., Çalik, P., Oliver, S.G., 2010. Metabolic flux analysis for recombinant protein production by Pichia pastoris using dual carbon sources. Effects of methanol feeding rate, Biotechnology and Bioengineering , 105, 317-329.

8.  Çelik, E. , Çalik, P., Oliver, S.G., 2009 . A structured kinetic model for recombinant protein production by Mut+ strain of Pichia pastoris , Chemical Engineering Science , 64, 5028-5035.

7.  Çelik, E., Çalik, P., Oliver, S.G., 2009. Fed-batch methanol feeding strategy for recombinant protein production by Pichia pastoris in the presence of co-substrate sorbitol , Yeast , 26, 473-484.

6.  Özdamar, T.H., Sentürk, B., Yilmaz, Ö.D., Çalik, G., Çelik, E. , Çalik, P., 2008. Expression system for recombinant human growth hormone production from Bacillus subtilis , Biotechnology Progress, 25, 75-84. 

5.  Çelik, E., Özbay, N., Oktar, N., Çalik, P., 2008. Use of biodiesel by-product crude glycerol as the carbon source for fermentation processes by recombinant Pichia pastoris. Industrial & Engineering Chemistry Research, 47, 2985-2990.

4.  Çalik, P., Orman, M.A., Çelik, E., Halloran, S.M ., Çalik, G., Özdamar, T.H ., 2008. Expression system for synthesis and purification of recombinant human growth hormone in Pichia pastoris and structural analysis by MALDI-ToF mass spectrometry . Biotechnology Progress , 24 ( 1), 221-226.

3.  Çelik, E., Çalik, P., Halloran, S.M., Oliver, S.G., 2007 . Production of recombinant human erythropoietin from Pichia pastoris and its structural analysis , Journal of Applied Microbiology , 103(6), 2084-2094.

2.   Çelik, E., Çalik P., 2004 . Bioprocess and oxygen transfer characteristics in beta-lactamase production by Bacillus specie s . Biotechnology Progress , 20(2), 491-499.

1. Çalik P., Çelik, E. , Telli, I.E, Oktar, C., Özdemir, E., 2003 . Protein based complex medium design for recombinant serine alkaline protease production by Bacillus subtilis . Enzyme and Microbial Technology , 33(7), 975-986.

 * Total number of citations to these articles (as of September 2021, WoS): 765, H-index: 14.

Book Chapter

1. Gündüz Ergün B., Hüccetogullari D., Öztürk S., Çelik E., Çalik P., 2019. Established and Upcoming Yeast Expression Systems. In: Recombinant Protein Production in Yeast. Ed: Gasser B, Mattanovich D, Humana Press Inc., ISBN: 978-1-4939-9023-8.

Conference Presentations:    

30. Koçer İ., Şahinbas D., Cilasun S., Çelik E., 5-7/3/2020. Production of ScFv Antibody Fragments and Their Applications, International Biotechnology Congres (BIO Türkiye-2020), Istanbul, Abstract Book, p39 (oral presentation).

29. Çagdas-Tunali B.,Çelik E., Türk M., 17-20/10/2019, Development of hyaluronic acid-polyethylenimine delivery system for gene silencing in cancer treatment, 24 th International Biomedical Science & Technology Symposium (BIOMED 2019), Izmir, Türkiye, Abstract Book, p78 (oral presentation).

28. Altun E., Çelik E., Yavuz Ersan H., 2-4/5/2018.Biodegradation Behavior of Two Different Chitosan Films under Controlled Composting Environment, Eurasia 2018 Waste Management Symposium, YTU Davutpasa Kongre Merkezi, Istanbul, 804-808 (poster).

27. Çagdas-Tunali, B., Çelik E ., Türk M., 12-14/5/2017. Hyaluronic acid-polyethylenimine delivery system for gene silencing, 22 nd International Biomedical Science & Technology Symposium (BIOMED 2017), Ankara, Türkiye, Abstract Book p065 (poster).

26. Akdogan M., Çelik E. 26-29/9/2016. Production and characterization of poly-3-hydroxybutyrate (PHB) under different dehydration techniques by Bacillus megaterium strain. 15th International Symposium on Biopolymers (ISBP2016), Madrid, Spain. Abstract Book p58 (poster).

25. Çelik E., 3-6/7/ 2016. Production of glycosylated recombinant proteins and phage particles in Escherichia coli. 17th European Congress on Biotechnology (ECB2016), Krakow, Poland. New Biotechnology 33, S44. (oral presentation).

24. Usta D.D., Salimi K., Koçer I., Çelik E., Tuncel A., 19-24/6/ 2016. A New Magnetic-silica Based Sorbent for Isolation of Green Fluorescent Protein by Immobilized Metal Affinity Chromatography. 44th International Symposium & Exhibit on High Performance Liquid Phase Separations and Related Techniques (HPLC2016), San Francisco, USA. Abstract Book (# P-Th-2432).

23. Çelik, E. 8-12/9/ 2015. The Bacterial Glycoengineering Toolbox, 4th Nanomedicine World Congress and 2nd International NanoBioTechnology Symposium, Köycegiz-Mugla, ( invited talk ).

22. Çelik E., DeLisa M.P., 15-20/9/ 2015. Glycoarrays constructed with engineered glycophage nanoparticles, XXIII International Symposium on Glycoconjugates, Split, Croatia, Glycoconjugate Journal 2015, 32, 5, p254 (oral presentation).

21. Koçer, I., Ersan, H.Y., Çelik, E. , 20-22/7/ 2015. Production and Characterization of the Recombinant Enzyme for Synthesis of Chitosan Biopolymer, International Conference on Chemical and Biochemical Engineering, Paris, France, (poster).

20. Çelik, E. , Gür, G., Bilgiç B., DeLisa, M.P. 20-22/7/ 2015. Glycan-protein interaction studies via GlycoPhage ELISA”, International Conference on Chemical and Biochemical Engineering, Paris, France, (poster)

19. Tatli, Z., DeLisa M., Çelik, E., 8-12/9/ 2015. Enhanced Production of Novel Cellulase Enzyme Towards Biofuels Sector By Recombinant Bacterium Escherichia coli , 4th Nanomedicine World Congress and 2nd International NanoBioTechnology Symposium, Köycegiz-Mugla, (poster).

18. Çelik, E. , 10-12/6/ 2015. Glycan arrays constructed with engineered glyco-phage nanoparticles for pathogen detection. 2 nd International Congress on Biosensors, Izmir, (oral presentation). E-abstract book: http://biosensor2015.gediz.edu.tr/page.aspx?id=14

17. Çelik, E., Gür, G., DeLisa, M.P., 7-10/9/ 2014. Engineering glycophages towards glycan microarrays. 10 th European Symposium on Biochemical Engineering Sciences (ESBES-IFIBIOP 2014), Lille, France. (poster #pE-8)

16. Koçer I., Çelik E., Ersan H. Y., 2-5/9/ 2014. Increasing the chitosan yield from microorganisms. 11 th National Chemical Engineering Conference, Eskisehir, Turkey, Abstract Book p.24-25. (poster)

15. Çelik, E., 27-29/8/ 2014. Production of biologicals by genetically engineered microorganisms, NanoBioTech-2014, Mugla, Turkey. ( invited talk )

14. Çelik, E., DeLisa, M.P., 2012. The GlycoPhage display system and its applications. New Biotechnology, 29, S162. 15th European Congress on Biotechnology (ECB-15), Istanbul, Turkey. (poster presentation, poster #5.0.10)

13. Eskitoros, M., Çelik, E., Çalik, P., 2012. Effect of co-carbon sources on erythropoietin production by Pichia pastoris . 9 th European Symposium on Biochemical Engineering Science (ESBES-9), Istanbul, Turkey. (poster presentation, poster #9.7)

12. Çelik, E., Fisher, A.C., Guarino, C., Mansell, T.J., DeLisa, M.P., 16-19/1/ 2011 . Glyco-phage display system for N -linked glycoproteins. International Conference on Biomolecular Engineering (ICBE2011), San Francisco, USA. Abstract Book, p45. (poster presentation) 

11. Çelik, E., Çalik, P., Oliver, S.G., 13–16/9/ 2009 . Recombinant protein production by Mut(+) strain of Pichia pastoris using dual carbon sources: methanol and sorbitol. New Biotechnology, 25: S60. 14th European Congress on Biotechnology. (ECB-14), Barcelona, Spain.  

10. Çelik, E., Çalik, P., Halloran, S.M., Oliver, S.G., 26-29/08/ 2008 . Pichia pastoris mayasi ile insan hormonu üretimi ve yapisal analizi. 8. Ulusal Kimya Mühendisligi Kongresi (UKMK-8), Malatya, Turkey. Abstract Book, p80-81. (oral presentation)

9.  Çelik, E., Özbay, N., Oktar, N., Çalik, P., 22-23/05/ 2008. Recombinant protein production in Pichia pastoris using byproduct of biodiesel production. Biopharmaceuticals: Why use yeasts? (Biotech2008), Wadenswil, Switzerland. Abstract Book, p52. (poster presentation)  

8. Çelik, E., Çalik, P., Halloran, M., Oliver, S.G. 2007 . Expression and structural characterization of recombinant human erythropoietin from Pichia pastoris. Journal of Biotechnology , 131 (2): S153-S154. 13 th European Congress on Biotechnology (ECB-13), Barcelona, Spain. (poster presentation) 

7.  Çelik, E., Çalik, P., Oliver S.G., 14-15/05/ 2007 . Production and metabolic flux analysis of recombinant human erythropoietin from Pichia pastoris . Somer Symposium Series 1 (SSS-1). Abstract Book, B-07. Turkey. (poster presentation) 

6. Çelik, E., Wishart, J., Zhang, N., Çalik, P., Oliver, S.G., 24-28/06/ 2006 . Investigation of Pichia pastoris as a system for recombinant erythropoietin production. 10 th International Symposium on the Genetics of Industrial Microorganisms (GIM2006), Abstract Book, P-256. Czech Republic. (poster presentation)

5.  Çelik, E., Çalik, P., 8-11/09/ 2004 . Effects of temperature on intracellular reaction rates in beta-lactamase production by Bacillus licheniformis. 5 th European Conference on Biochemical Engineering Science (ESBES-5), Abstract Book, P-90, Germany. (poster presentation).  

4.   Arifoglu, M., Çelik, E., Çalik, P., Çalik, G., 05-09/07/ 2004. Bacillus licheniformis ile beta-laktamaz üretimi için tanimlanmis ortamda oksijen aktarimi etkilerinin arastirilmasi. XVIII. National Chemistry Conference, Kars, Turkey.  

3. Arifoglu, M., Çelik, E., Çalik, P., Çalik, G., 07-10/09/ 2004 . Oksijen aktariminin beta-laktamaz üretimine etkisinin arastirilmasi. 6. Ulusal Kimya Mühendisligi Kongresi, Izmir.

2. Çelik, E., Çalik, P., 24-29/08/ 2003 . Effects of induction strategy and medium composition on beta-lactamase production by Bacillus species. 11 th European Congress on Biotechnology (ECB-11), Abstract Book, p234, Switzerland.

1. Çelik, E., Çalik, P., 13-15/05/ 2003 . Production of b-lactamase by Bacillus species: effect of medium composition. 3 rd Eastern Mediterranean Chemical Engineering Conference (EMCC-3), Greece. (poster presentation)