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Article # : SC07

Sema Çalış, Ph.D.

Professor

A non-antibiotic antimicrobial mixture (C31G): evaluation of the antimicrobial efficiency of C31G on vaginal cultures

Sema Calis*, Nuran Yulug**, Murat Sumnu*, Ali Ayhan***, A. Atilla Hincal*

  * Department of Pharmaceutical Technology, Faculty of Pharmacy,

 ** Department  of  Microbiology  Faculty of  Medicine,

***Department  of   Gynecology,  Faculty   of   Medicine, Hacettepe University 06100 Ankara-Turkey

Summary

Minimum inhibitory concentrations and the effective period for cidal concentrations of an amphoteric surfactant mixture (C31G) were determined on 13 microorganisms (common bacteria, strains ATCC, and fungi) by microtiter dilution procedure. Also the antimicrobial efficiency of this composition (C31G) was evaluated on105 culture samples which were obtained from (Turkish) patients having vaginal infections. E. coli was found to be the most frequently observed microorganism (45.45%) in these samples and C31G was determined to be active on microorganisms obtained from vagina at low concentrations in a short time.

Key words

Vaginal cultures; Antimicrobial efficiency; Amphoteric surfactant; Antimicrobial compound; Minimum inhibitory concentrations.