Publications

 

Ozturk K, Caban S, Kozlu S, Kadayifci E, Yerlikaya F, Capan Y.;

The influence of technological parameters on the physicochemical properties of blank PLGA nanoparticles.

Pharmazie, 65(9):665-9, 2010

 

Yerlikaya F, Aktas Y, Capan Y;

LC-UV Determination of Melatonin from Chitosan Nanoparticles,

Chromatographia, 9-10 (71) 967-970 , 2010

 

Karatas H, Aktas Y, Gursoy-Ozdemir Y, Bodur E, Yemisci M, Caban S, Vural A, Pinarbasili O, Capan Y, Fernandez-Megia E, Novoa

Carballal R, Riguera R, Andrieux K, Couvreur P, Dalkara T,

A nano-medicine transports a peptide caspase-3 inhibitor across the blood-brain barrier and provides neuroprotection,

J. Neuroscience 29 (44):13761-9, 2009

 

A. Aktaş, B. Giray, Y. Çapan, D. Menemenlioğlu, M. Hayran, G. İkinci, İ. Vural,

Microbiological and clinical comparison of chlorhexidine buccoadhesive tablet and chlorhexidine mouthrinse,

J. Drug Del. Sci. Tech., 19 (5) 353-357, 2009

 

Pinarbasli, O., Aktas, Y., Dalkara, T., Andrieux, K., Alonso, M.J., Fernandez-Megia,

E., R. Novoa-Carballal, R., Riguera, R., Couvreur, P., Capan, Y.

Preparation and Evaluation of PBN-Encapsulated Chitosan and PEGylated Chitosan Nanoparticles,

Pharmazie, 64(7):436-9, 2009

 

M. Cetin, Y. S. Youn, Y. Capan, K. C. Lee

Preperation and characterization of salmon-calcitonin biotin conjugates

AAPS Pharm.Sci.Tech., 9 (4) pp1191-1197, 2008

 

M. Cetin, I. Vural, Y. Capan, A.A. Hincal

Preperation and characterization of BSA loaded alginate microspheres

FABAD Journal of Pharmaceutical Sciences, 32 (3) pp103-107, 2007

 

Cetin, M., Aktas, Y., Vural, I., Capan, Y.;

Preparation and In Vitro Evaluation of bFGF-Loaded Chitosan Nanoparticles;        

Drug Delivery; 14, 1–5, 2007

 

Na DH, Faraj J, Capan Y, Leung KP, DeLuca PP.

Stability of antimicrobial decapeptide (KSL) and its analogues for delivery in the oral cavity.

Pharm Res 24, 1544-50, 2007

 

JA. Faraj , R. Dorati , A. Schoubben, D. Worthen, F. Selmin,Y. Capan, K. Leung, P P  DeLuca

The Development of a Peptide Containing Chewing Gum as a Sustained ReleaseAntiplaque Antimicrobial Delivery System.

AAPS PharmSci.Tech. 8 (1), 26, 2007

 

M.Yemisci, İ.Vural, S. Bozdağ, M. Çetin, F. Söylemezoğlu, Y. Çapan, T. Dalkara,

Treatment of Malignant Glioma with Mitoxantrone-Loaded PLGA Microspheres,

Neurosurgery. 59 ,1296, 2006

 

Aktas Y, Yemisci M, Andrieux K, Gursoy RN, Alonso MJ, Fernandez-Megia E,

Novoa-Carballal R, Quinoa E, Riguera R, Sargon MF, Celik HH, Demir AS, Hincal AA, Dalkara T, Capan Y, Couvreur P.

Development and brain delivery of chitosan-PEG nanoparticles functionalized with the monoclonal antibody OX26.

Bioconjug. Chem.  16,1503, 2005

 

D. H.Na, J. Faraj, Y.Capan, K.P. Leung, P.P. DeLuca

Chewing gum of antimicrobial decapeptide (KSL) as a sustained antiplaque agent.Preformulation study

J Control Release 107 ,122, 2005

 

M. Cetin  , Y.Capan , İ.Vural  , L.A.Dogan  , D.Guc  , A.A.Hincal , P.Wehrlé , T.Dalkara , P.P.DeLuca,

Preparation and Characterization of bFGF and BSA Loaded Microspheres,

J.Drug Del. Sci. Tech.15,371, 2005

 

A.C. Kilic, Y. Capan, I. Vural, R. N. Gursoy, T. Dalkara, A. Cuine, A. Hincal,

Preparation and characterization of PLGA nanospheres for the targeted delivery of NR2B-spesific antisense oligonucleotides to the NMDA receptors in the brain

J Microencapsul.  22,633, 2005

 

Y.Aktas, K.Andrieux, M.J.Alonso, P.Calvo, R.N.Gursoy, P.Couvreur, Y.Capan

Preparation and in vitro evaluation of chitosan nanoparticles containing a caspase inhibitor

Int J Pharm. 298,378, 2005

 

S. Bozdağ, Y. Çapan, İ.Vural, T. Dalkara, A.L. Dogan, D. Guc, A. A. Hıncal, P.P.DeLuca,

Formulation and In Vitro Cytotoxicity of Mitoxantron- Loaded Biodegradable Microspheres on  Rat Glioma Cells

J. Drug Del. Sci. Tech., 15, 201, 2005

 

S. Bozdağ, Y. Çapan, İ. Vural. A.A.Hıncal

Method Validation in Determination of Mitoxantrone by HPLC

Acta Pharmaceutica Turcica.,46:43, 2004

 

M.Cetin,Y.Capan

Brain Drug targeting

J.Fac.Pharm. Ankara,33,287, 2004

 

S. Bozdağ, Y. Çapan, İ.Vural, T. Dalkara, A.L. Dogan, D. Guc, A. A. Hıncal,

In vitro Cytotoxıcıty of Mitoxantron-Incorporated Albumin Microspheres on Acute Promyelocytic Leukemia Cells

Journal of Microencapsulation, 21,751, 2004

 

R. Elqidra, N. Ünlü, Y. Çapan, G. Şahin, T. Dalkara, A. A. Hıncal

Effect of polymorphism on in vitro- in vivo properties of carbamazepine conventional tablets.

J. Drug Del. Sci. Tech., 14,147, 2004

 

Y. Çapan, G. Jiang, S. Giovagnoli, K. Na, P. P. DeLuca

Preparation and characterization of poly(D,L- lactide-co-glycolide) microspheres for controlled release of human growth hormone 

AAPS PhamSciTech,  4, 236, 2003

 

S. Bozdag, Y. Capan, I. Vural, A.A. Hincal, P.P DeLuca

Mitoxantrone loaded poly(DL-lactide-co-glycolide) microspheres for treatment of brain tumors I. formulation and release characteristics

Technology and Health Care, 10 (3-4) pp353-355, 2002

 

G. İkinci, Y. Çapan, S. Şenel, E. Alaaddinoğlu, T. Dalkara, A. A. Hıncal

In vitro/in vivo studies on buccal bioadhesive tablet formulation of carbamazepine

Pharmazie,  55,762, 2000

 

H.Selek, Y.Çapan, H.S.Kaş

Starch Microspheres: Importance, Preparation and Applications

FABAD J. Pharm. Sci., 24, 31, 1999

 

Y.Çapan, B.H. Woo, S. Gebrekidan, S.Ahmed, P.P.DeLuca

Stability of poly(L-Lysine) complexed plasmid DNA.

Pharm.Dev. Tech. 4, 491, 1999

 

Y.Çapan, B.H. Woo, S. Gebrekidan, S.Ahmed, P.P.DeLuca

Influence of formulation parameters on the characteristics of poly(D,L- lactide-co-glycolide) microsphere containing poly(L-lysine)complexed plasmid DNA.

J. Control. Rel. 60, 279, 1999

 

Y.Çapan, B.H. Woo, S. Gebrekidan, S.Ahmed, P.P.DeLuca.

Preparation and characterization of poly (D,L-lactide-co-glycolide) microspheres for controlled release of plasmid DNA.

Pharm. Res. 16, 509, 1999

 

G.İkinci, Y.Çapan, S.Şenel, T. Dalkara, A.A. Hıncal

Formulation and In Vitro-In Vivo investigation of carbamazepine controlled release matrix tablets

Pharmazie, 54, 139, 1999

 

Y. Yazıksız-İşcan, Y, Çapan, S. Şenel, M.F. Şahin, S. Kes, D. Duchêne, A. Atilla  Hıncal.

Formulation and In vitro In vivo Evaluation of Buccal Bioadhesive Captopril Tablets

STP Pharma, 8, 357, 1998

 

S. Şenel, Y. Çapan, M.F. Sargon, C.B. Giray, A.A. Hıncal

Histological and Bioadhesion Studies on Buccal Bioadhesive Tablets Incorporated with a Penetration Enhancer, Sodium Glycodeoxycholate.

Int. J. Pharm., 170, 239, 1998

 

S. Şenel, D. Duchêne, A.A. Hıncal, Y. Çapan, G. Ponchel 

In Vitro Studies on Enhancing Effect of Sodium Glycocholate on Transbuccal Permeation of Morphine Hydrochloride.

J. Control. Rel., 51, 107, 1998 

 

S. Şenel, Y. Çapan, M.F. Sargon, G. İkinci, D. Şolpan , O. Güven, H.E. Bodde, A.A.Hıncal    

Enhancement  of  Transbuccal Permeation of Morphine Sulfate by Sodium Glycodeoxycholate In Vitro.

J. Control. Rel., 45, 153, 1997

 

B. Taylan, Y. Çapan, O. Güven, S. Kas, A. A. Hıncal

Design and Evaluation of Sustained-Release and Buccoadhesive Propranolol Hydrochloride Tablets.

J. Control. Rel., 38, 11, 1996

 

F.S. Farshi, Y. Çapan, S. Kes, A.A. Hıncal

Formulation  and  Comparative  Bioavailability  of  Conventional  and  Sustained-Release  Furosemide  Tablets.

S.T.P. Pharma Sciences, 5, 361, 1995

 

F.S. Farshi, Y. Çapan, A.A. Hıncal

Topographical  Dissolution  Characterization  for  Sustained-Release  Furosemide Tablets.

Acta Pharmaceutica Turcica., 36, 118, 1994

 

Ş. Anlar, Y. Çapan, O. Güven, A. Göğüş, T. Dalkara, A. A. Hıncal

Formulation and In vitro- In vivo Evaluation of Buccoadhesive Morphine Sulphate Tablets.

Pharm. Res., 11, 231, 1994

 

Ş. Anlar, Y. Çapan, A. A. Hıncal

Physico-Chemical and Bioadhesive Properties of  Polyacrylic Acid Polymers.

Pharmazie, 48, 285, 1993

 

Y. Çapan, N. Çapan, H. S. Kaş, Ş. Atikcan, Y. Başer, A. A. Hıncal

Formulation and Efficiency of Sustained Release Theophylline Tablets

S.T.P. Pharma Sciences, 2, 169, 1992

 

S. Şenel, Y. Çapan, A. A. Hıncal

Factors Affecting the Formulation of Sustained Release Potassium Chloride Tablets

Pharmazie, 46, 792, 1991

 

S. Şenel, Y. Çapan, T. Dalkara, N. İnanç, A. A. Hıncal

Formulation, Bioavailability and Pharmacokinetics of  Sustained Release Potassium Chloride Tablets.

Pharm. Res., 8, 1313, 1991

 

K. Çiftçi, Y. Çapan, A. A. Hıncal

Evaluation of Sustained Release Lithium Carbonate Tablets from Urine

S.T.P. Pharma Sciences, 1, 272, 1991

 

Y. Çapan, K. Çiftçi, A.A. Hıncal

Influence of Filler Excipients on the Release Rate  of Sustained Release Lithium Carbonate Tablets.

Eur. J. Pharm. Biopharm., 37, 14, 1991

 

Y. Çapan, S. Kaş, L. Öner, F. Bulut-Öner, A. A. Hıncal

Sustained Release Isoniasid Tablets  II. In Vivo Evaluation

S.T.P. Pharma Sciences, 6, 460, 1990

 

K. Çiftçi, Y. Çapan, O. Öztürk, A. A. Hıncal  

Formulation and In Vitro- In Vivo Evaluation of   Sustained Release Lithium Carbonate Tablets.

Pharm. Res. , 7, 359, 1990

 

F. Bulut-Öner, Y. Çapan, S. Kaş, L. Öner, A. A. Hıncal

Sustained Release Isoniasid Tablets. I. Formulation and In Vitro Evaluation

Farmaco., 44 ,739, 1989

 

Y. Çapan, S. Şenel, S. Çalış, S. Takka, A. A. Hıncal

Formulation and In Vitro- In Vivo Evaluations on Sustained Release Acetylsalicylic Acid Tablets.

Pharm. Ind., 51, 443, 1989

 

Y. Çapan

Influence of Technological Factors on Formulation of Sustained Release Tablets.

Drug Dev. Ind. Pharm., 15, 927, 1989

 

Y. Çapan

Les Formes Pharmaceutiques Orales Solides  à Libération Programée.

Sci. Techn. Pharm., 13, 43, 1984

 

Y. Çapan

Formulation de Comprimés de Nitrofurantoin à   Libération Modifiée Obtenus par Compression Directe

Labo-Pharma-Probl. Tech., 31, 837, 1983

 

N. Ünlü, Y. Çapan, N. Yuluğ

Formulation Studies of the Wetting Solutions for Hard Contact Lenses

Microbiyol. Bull., 15, 179, 1981

Journal Articles (Refereed)

Journal Articles (Not Refereed)

M.Çetin , Y. Çapan

bFGF ( Basic Fibroblast Growth Factor ) and a novel approach to its formulations

H.U. J.  Fac. Pharm., 24, 107 (2004 )

 

S. Bozdağ, İ. Vural, Y. Çapan, T. Dalkara

Application of Drug Carrier Systems for Brain Tumor Therapy

FABAD J. Pharm. Sci., 27, 89 (2002)

 

R. Elqidra, N. Ünlü, Y.Çapan, A.A. Hıncal

Effect of Polymorphism on Carbamazepine Tablet Characteristics

H.U. J.  Fac. Pharm., 21, 83 (2001)

 

İ. Yenice, S. Çalış, Y. Çapan

Quality Control of Conventional and Controlled-Release Carbamazepine Tablets Available in Turkish Market

H.U.J. Fac. Pharm.,20, 45 (2000)

 

Y. Yazıksız, Y. Çapan, A.A.Hıncal

Buccal Adhesive Drug Delivery Systems

FABAD J. Pharm. Sci., 22, 65 (1997)

 

Y.Çapan

Controlled-Release Oral Solid Dosage Forms, General Principles

Posyon, 5, 117 (1996)

 

Y. Çapan

Recent Pharmacopeial Controls Used for the Evaluation of Solid Dosage Forms - II

POSYON, 5, 71 (1996)

 

F.S. Farshi, Y. Çapan, A.A. Hıncal,

Bioavailability File: Furosemide

FABAD J. Pharm. Sci., 21, 87 (1996)

 

Y. Çapan

Recent Pharmacopeial Controls Used for the Evaluation of Solid Dosage Forms - I.

POSYON, 5, 36 (1996)

 

Y. Çapan

Novel Approaches in Pharmaceutical Dosage Forms

Rapor, 8, 4 (1995)

 

Y. Çapan

Quality Assurance and ISO 9000 in Pharmaceutical Industry.

POSYON, 4, 44 (1995)

 

Y.Çapan

ISO 9000 Standards and GMP

POSYON, 3, 12 (1994)

 

Y. Çapan

Properties and Evaluation of Sustained Release Tablets.

FABAD J. Pharm. Sci., 18, 27( 1993)

 

Ş. Anlar, Y. Çapan, A. A. Hıncal

Bioadhesive Controlled Release Systems II. Experimental Methods for Evaluation of  Bioadhesive Bond Strength of 

Polymers with Mucus.

FABAD J. Pharm. Sci., 17, 277 (1992)

 

Ş. Anlar, Y. Çapan, A. A. Hıncal

Bioadhesive Controlled Release Systems I Fundamentals of Bioadhesion.

FABAD J. Pharm. Sci., 17, 203 (1992)

 

S.Şenel, Y.Çapan, A.A.Hıncal

Applications of Thermal Analysis in Pharmaceutics.

FABAD J. Pharm. Sci., 17, 45 (1992)

 

Y. Çapan, A. A. Hıncal

The Physics of Tablet Compression II. The Strength of Tablets.

FABAD J. Pharm. Sci., 11, 82 (1986)

 

Y. Çapan, A. A. Hıncal

The Physics of Tablet Compression I.

FABAD J. Pharm. Sci. 9, 93 (1984)

 

T. Eldem, Y. Çapan

Formulation Studies on Sustained Release Nitrofurantoin Tablets.

Bull. Hacettepe University Faculty of Pharmacy  4, 9 (1984)

 

Y. Çapan

Le Choix des Excipients en Compression Directe à l'Aide des Energies de

Compression

FABAD J. Pharm. Sci. , 9, 108 (1984)

 

N. Ünlü, Y. Çapan, N. Yuluğ

Formulation Studies of the Wetting Solutions for Hard Contact Lenses II.

FABAD  J. Pharm. Sci., 7, 125 (1982)

Book Chapters

-     S. Şenel, Y. Çapan and A. A. Hıncal

Factors Affecting the Formulation of Sustained Release Potassium Chloride Tablets

In: PHARMACEUTICAL TECHNOLOGY

Controlled Drug Release Vol. 2 J. I. Wells and Rubinstein (Eds.)

pp. 34-43, Ellis Harwood, New York, 1991 

 

-     Y. Çapan,

      Pharmaceutical Factors Affecting Bioavailability and Bioequivalance.

      In: BIOAVAILABILITY AND BIOEQUIVALANCE

      L. Öner, M. Şumnu, A.A.Hıncal (Eds.)

      Şafak Matbaası, Ankara, 1995.

 

-     S. Şenel, Y. Çapan, M.F. Sargon, D. Solpan, O. Güven, H.E. Boddé, A.A. Hıncal,

Enhancing Effect of Sodium Glycodeoxycholate on Diffusion Rate of Morphine 

      Sulfate Through Buccal Epithelium

      In: P. Couvreur, D.D. Duch(ne, I. Kalles, ( Eds),

      pp. 441- 445, MINUTES, Formulation of Poorly-Available Drugs for Oral Administration,

      European Symposium, Editions de Santé Publishers, Paris, 1996. 

 

-     Y. Çapan

Kontrollü Salım Sistemlerinin Salım Mekanizmaları ve Kullanılış Yolları (Release 

      Mechanisms of  Controlled  Release Systems and Administrations Routes )                                       

      In: Kontrollü Salım Sistemleri (Controlled Release Systems)

      A. Gürsoy (Ed)

      pp.41-64, Elma Bilgisayar Basım ve Ambalaj San. Tic. Ltd. Şti, İstanbul, 2002.

 

-     Y. Çapan

      Mukozaya Yapışan Sistemler (Mucoadhesive Systems )

      In: Kontrollü Salım Sistemleri  (Controlled Release Systems)

      A. Gürsoy (Ed)

      pp.177-196, Elma Bilgisayar Basım ve Ambalaj San. Tic. Ltd. Şti, İstanbul, 2002.

 

-     Y. Çapan

Çözünürlük ve çözünme hızına etki eden faktörler (Solubility and factors effecting solubility rate)

      In: Farmasötik Teknoloji (Pharmaceutical Technology)

      A. Gürsoy (Ed.)

 pp. 85-96, Piksel Bilişim Matbaacılık Reklamcılık ve Filmcilik Hizmetleri Ltd. Şti., İstanbul, 2004.

 

-     Y. Çapan

      Biyoyararlanım (Bioavailability)

      In: Farmasötik Teknoloji (Pharmaceutical Technology)

      A. Gürsoy (Ed.)

pp.159-168, Piksel Bilişim Matbaacılık Reklamcılık ve Filmcilik Hizmetleri Ltd. Şti., İstanbul, 2004.

 

-     O. Pinarbasli, Y. Aktas, Y. Capan

      Development and Validation of an Analytical Method for The Determination        of PBN  from

     Chitosan Nanoparticles

      In: Advances in Chitin Science

      S.Senel, K.M. Varum, M.M. Sumnu, A.A. Hincal (Eds),

pp: 370-375, . Alp Ofset, Ankara, 2007